Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway

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Gomes-Gonçalves, Alexandra; Van Genechten, Wouter; Ataíde, Patricia; Barata-Antunes, Cláudia; Ghasemi, Faezeh; Casal, Margarida; Teixeira, Miguel C.; Ariño, Joaquín; Brown, Alistair J. P.; Van Dijck, Patrick; Paiva, Sandra, 2025, "Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway", https://doi.org/10.34622/datarepositorium/VWHFGK, Repositório de Dados da Universidade do Minho, V1, UNF:6:Uc2maDQk9d3HlXPVfYcX4g== [fileUNF]

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Description	Comparison of mRNA levels by RNA-Seq between Candida albicans yeast cells grown in RPMI medium in the presence of lactate, and at different extracellular pHs (pH 5; pH 7.0) (replicas per different pH and timepoint: n=3 at 1 h; and n = 1 at 0.5, 2, and 4 h - 30 samples in total)
Subject	Other
Keyword	Candida albicans, carboxylic acids, lactate, iron reductive pathway, iron

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	1 to 3 of 3 Files	Original Format Archival Format (.tab)
	00_Readme.txt Plain Text - 3.9 KB - Jun 3, 2025 - 1 Download MD5: 2d5872e2367483cdfd71bfd0528f7fb5	Download
	gene_FPKM.tab Tabular Data - 1.2 MB - Jun 3, 2025 - 0 Downloads 31 Variables, 6263 Observations - UNF:6:/wdpezhETu4T2zXGyiZdpQ== excel file with "Reads Per Kilobase Million" data for each sample	View Data Original File Format (MS Excel Spreadsheet) Tab-Delimited RData Format Variable Metadata Data File Citation RIS EndNote XML BibTeX
	Relative_Abundance_ALL_GENES.tab Tabular Data - 4.4 MB - Jun 3, 2025 - 0 Downloads 39 Variables, 5887 Observations - UNF:6:E/O5WncR9CMargfSRuM2ow== excel file with the variance stabilised transforms of each gene in the different conditions and timepoints	View Data Original File Format (MS Excel Spreadsheet) Tab-Delimited RData Format Variable Metadata Data File Citation RIS EndNote XML BibTeX

Citation Metadata

Dataset Persistent ID	doi:10.34622/datarepositorium/VWHFGK
Publication Date	2025-06-03
Title	Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway
Author	Gomes-Gonçalves, Alexandra (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho) - ORCID: 0000-0003-4595-5575 Van Genechten, Wouter (Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, K.U. Leuven, Leuven, Belgium) Ataíde, Patricia (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho) Barata-Antunes, Cláudia (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho) Ghasemi, Faezeh (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho) Casal, Margarida (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho) Teixeira, Miguel C. (Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal) Ariño, Joaquín (Institut de Biotecnologia i Biomedicina & Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona) Brown, Alistair J. P. (MRC Centre for Medical Mycology at the University of Exeter, Exeter, UK) Van Dijck, Patrick (Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, K.U. Leuven, Leuven, Belgium) Paiva, Sandra (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)
Contact	Use email button above to contact. Gonçalves, Alexandra (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho) Paiva, Sandra (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)
Description	Comparison of mRNA levels by RNA-Seq between Candida albicans yeast cells grown in RPMI medium in the presence of lactate, and at different extracellular pHs (pH 5; pH 7.0) (replicas per different pH and timepoint: n=3 at 1 h; and n = 1 at 0.5, 2, and 4 h - 30 samples in total)
Subject	Other
Keyword	Candida albicans carboxylic acids lactate iron reductive pathway iron
Grant Information	Fundação para a Ciência e Tecnologia: doi.org/10.54499/PTDC/BIA-MIC/5246/2020
Depositor	Gonçalves, Alexandra
Deposit Date	2025-06-03

Life Sciences Metadata

Design Type	Not Specified
Factor Type	Genetic Characteristics; Other; Time Point
Organism	Other
Other Organism	Candida albicans
Measurement Type	Other
Other Measurement Type	RNA-Seq

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