Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway (ICPSR doi:10.34622/datarepositorium/VWHFGK)

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Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
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Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway

doi:10.34622/datarepositorium/VWHFGK

Repositório de Dados da Universidade do Minho

2025-06-03

1

Gomes-Gonçalves, Alexandra; Van Genechten, Wouter; Ataíde, Patricia; Barata-Antunes, Cláudia; Ghasemi, Faezeh; Casal, Margarida; Teixeira, Miguel C.; Ariño, Joaquín; Brown, Alistair J. P.; Van Dijck, Patrick; Paiva, Sandra, 2025, "Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway", https://doi.org/10.34622/datarepositorium/VWHFGK, Repositório de Dados da Universidade do Minho, V1, UNF:6:Uc2maDQk9d3HlXPVfYcX4g== [fileUNF]

Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway

doi:10.34622/datarepositorium/VWHFGK

Gomes-Gonçalves, Alexandra (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)

Van Genechten, Wouter (Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, K.U. Leuven, Leuven, Belgium)

Ataíde, Patricia (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)

Barata-Antunes, Cláudia (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)

Ghasemi, Faezeh (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)

Casal, Margarida (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)

Teixeira, Miguel C. (Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal)

Ariño, Joaquín (Institut de Biotecnologia i Biomedicina & Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona)

Brown, Alistair J. P. (MRC Centre for Medical Mycology at the University of Exeter, Exeter, UK)

Van Dijck, Patrick (Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, K.U. Leuven, Leuven, Belgium)

Paiva, Sandra (Centre of Molecular and Environmental Biology, Department of Biology, University of Minho)

doi.org/10.54499/PTDC/BIA-MIC/5246/2020

Repositório de Dados da Universidade do Minho

Gonçalves, Alexandra

Paiva, Sandra

Gonçalves, Alexandra

2025-06-03

Other, Candida albicans, carboxylic acids, lactate, iron reductive pathway, iron

Comparison of mRNA levels by RNA-Seq between Candida albicans yeast cells grown in RPMI medium in the presence of lactate, and at different extracellular pHs (pH 5; pH 7.0) (replicas per different pH and timepoint: n=3 at 1 h; and n = 1 at 0.5, 2, and 4 h - 30 samples in total)

<a rel="license" href="http://creativecommons.org/licenses/by/4.0/"><img alt="Creative Commons Licence" style="border-width:0" src="https://i.creativecommons.org/l/by/4.0/88x31.png" /></a><br />This work is licensed under a <a rel="license" href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>.

• Number of cases: 6263

• No. of variables per record: 31

• Type of File: text/tab-separated-values

UNF:6:/wdpezhETu4T2zXGyiZdpQ==

• Number of cases: 5887

• No. of variables per record: 39

• Type of File: text/tab-separated-values

UNF:6:E/O5WncR9CMargfSRuM2ow==

• geneid - geneid
• 010hpH5bNoLacS1.xls - 010hpH5bNoLacS1.xls
• 020hpH5cNoLacS2.xls - 020hpH5cNoLacS2.xls
• 030hpH5bLacS3.xls - 030hpH5bLacS3.xls
• 040hpH7bNoLacS4.xls - 040hpH7bNoLacS4.xls
• 050hpH7cNoLacS5.xls - 050hpH7cNoLacS5.xls
• 060hpH7bLacS6.xls - 060hpH7bLacS6.xls
• 0730pH5bNoLacS7.xls - 0730pH5bNoLacS7.xls
• 0830pH5bLacS8.xls - 0830pH5bLacS8.xls
• 0930pH7bNoLacS9.xls - 0930pH7bNoLacS9.xls
• 1030pH7bLacS10.xls - 1030pH7bLacS10.xls
• 111hpH5aNoLacS11.xls - 111hpH5aNoLacS11.xls
• 121hpH5bNoLacS12.xls - 121hpH5bNoLacS12.xls
• 131hpH5cNoLacS13.xls - 131hpH5cNoLacS13.xls
• 141hpH5aLacS14.xls - 141hpH5aLacS14.xls
• 151hpH5bLacS15.xls - 151hpH5bLacS15.xls
• 161hpH5cLacS16.xls - 161hpH5cLacS16.xls
• 171hpH7aNoLacS17.xls - 171hpH7aNoLacS17.xls
• 181hpH7bNoLacS18.xls - 181hpH7bNoLacS18.xls
• 191hpH7cNoLacS19.xls - 191hpH7cNoLacS19.xls
• 201hpH7aLacS20.xls - 201hpH7aLacS20.xls
• 211hpH7bLacS21.xls - 211hpH7bLacS21.xls
• 221hpH7cLacS22.xls - 221hpH7cLacS22.xls
• 232hpH5bNoLacS23.xls - 232hpH5bNoLacS23.xls
• 242hpH5bLacS24.xls - 242hpH5bLacS24.xls
• 252hpH7bNoLacS25.xls - 252hpH7bNoLacS25.xls
• 262hpH7bLacS26.xls - 262hpH7bLacS26.xls
• 274hpH5bNoLacS27.xls - 274hpH5bNoLacS27.xls
• 284hpH5bLacS28.xls - 284hpH5bLacS28.xls
• 294hpH7bNoLacS29.xls - 294hpH7bNoLacS29.xls
• 304hpH7bLacS30.xls - 304hpH7bLacS30.xls
• A - A
• RelativeAbundance-ALLGENES - RelativeAbundance-ALLGENES
• C - C
• D - D
• E - E
• F - F
• G - G
• H - H
• I - I
• J - J
• K - K
• L - L
• M - M
• N - N
• O - O
• P - P
• Q - Q
• R - R
• S - S
• T - T
• U - U
• V - V
• W - W
• X - X
• Y - Y
• Z - Z
• AA - AA
• AB - AB
• AC - AC
• AD - AD
• AE - AE
• AF - AF
• AG - AG
• AH - AH
• AI - AI
• AJ - AJ
• AK - AK
• AL - AL
• AM - AM

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Variable Format: character

Notes: UNF:6:qt1gW8teLdmxSR/K4oipNA==

f6956 Location:

Summary Statistics: Max. 53243.68; Valid 6263.0; Min. 0.0; Mean 236.02171323646817; StDev 1207.0358061728102

Variable Format: numeric

Notes: UNF:6:5DFY0r8O/El0Zs9Q6G7MPg==

f6956 Location:

Summary Statistics: Max. 65071.69; Valid 6263.0; Mean 231.68874181702054; Min. 0.0; StDev 1308.9473666093322

Variable Format: numeric

Notes: UNF:6:EdKV27PH32L/ivaoVW6uoA==

f6956 Location:

Summary Statistics: Min. 0.0; Max. 58761.89; Valid 6263.0; StDev 1234.1369960966838; Mean 237.0486492096439;

Variable Format: numeric

Notes: UNF:6:IpwNRygyYcI942lOmUejng==

f6956 Location:

Summary Statistics: Min. 0.0; Valid 6263.0; StDev 1042.9219381340945; Mean 243.3205460641865; Max. 37742.02;

Variable Format: numeric

Notes: UNF:6:2tiPY+iMyNN/FXFiEzPQuw==

f6956 Location:

Summary Statistics: StDev 1117.425087371319; Mean 249.02540156474538; Min. 0.0; Valid 6263.0; Max. 44100.54;

Variable Format: numeric

Notes: UNF:6:3OAQlhFHKw5JnOnPMiJ/Ug==

f6956 Location:

Summary Statistics: StDev 1066.022336821128; Valid 6263.0; Max. 37331.47; Mean 248.18702379051575; Min. 0.0;

Variable Format: numeric

Notes: UNF:6:N4BRRwkPV6cSzLXkoM3l8A==

f6956 Location:

Summary Statistics: Valid 6263.0; Mean 230.33467667252123; Max. 63826.46; StDev 1251.9915236812076; Min. 0.0;

Variable Format: numeric

Notes: UNF:6:EYWBGhM2NXuCUUK4bSVTIQ==

f6956 Location:

Summary Statistics: Mean 246.5367539517803; Min. 0.0; Max. 57168.76; Valid 6263.0; StDev 1242.693765915373

Variable Format: numeric

Notes: UNF:6:3/l61Mq5WGCPT519ITz3ZQ==

f6956 Location:

Summary Statistics: Mean 249.204366916813; Max. 39542.94; StDev 1103.9821638015235; Valid 6263.0; Min. 0.0;

Variable Format: numeric

Notes: UNF:6:SoxDsVkxkrquOjbcfLUr2A==

f6956 Location:

Summary Statistics: Valid 6263.0; Mean 248.46344722976207; Min. 0.0; StDev 1117.2429804785647; Max. 39565.93

Variable Format: numeric

Notes: UNF:6:4h7e9vu9tIKGcSqFWs1AEw==

f6956 Location:

Summary Statistics: Valid 6263.0; Max. 53640.68; StDev 1311.2197037321948; Min. 0.0; Mean 250.37695832668047

Variable Format: numeric

Notes: UNF:6:pgiiA/zTwpNcZF3fUCuUtg==

f6956 Location:

Summary Statistics: Mean 234.25775666613436; Max. 66688.78; Min. 0.0; StDev 1265.9527364787427; Valid 6263.0;

Variable Format: numeric

Notes: UNF:6:Sn4OdGdxBSrdSE6XnKBEew==

f6956 Location:

Summary Statistics: Min. 0.0; StDev 1327.263649268019; Mean 233.45191441801055; Valid 6263.0; Max. 71655.08

Variable Format: numeric

Notes: UNF:6:cohgLhTXpSHR2UATgmbr2g==

f6956 Location:

Summary Statistics: Mean 235.43450582787813; StDev 1255.8611263227162; Min. 0.0; Valid 6263.0; Max. 55063.19;

Variable Format: numeric

Notes: UNF:6:rbIsAnQ0UJQo01Y0I+SsvQ==

f6956 Location:

Summary Statistics: Valid 6263.0; Min. 0.0; Mean 244.02010538080788; StDev 1242.4985410845043; Max. 43544.76;

Variable Format: numeric

Notes: UNF:6:CGetR1FgWD28AkREC3rqCg==

f6956 Location:

Summary Statistics: Min. 0.0; Valid 6263.0; Mean 241.00908669966472; Max. 68798.77; StDev 1337.1320484458365;

Variable Format: numeric

Notes: UNF:6:sVYAjWT1dxTSgZWNv2oxKQ==

f6956 Location:

Summary Statistics: Mean 255.97712757464464; Valid 6263.0; Max. 47876.03; Min. 0.0; StDev 1203.9834314530829;

Variable Format: numeric

Notes: UNF:6:3svVKfmAb1vzzzU76Usygw==

f6956 Location:

Summary Statistics: Valid 6263.0; Min. 0.0; Max. 44864.23; Mean 251.79250039916974; StDev 1181.2007354462978;

Variable Format: numeric

Notes: UNF:6:CGWefvj6+cT+rivdcqNbIA==

f6956 Location:

Summary Statistics: Min. 0.0; StDev 1198.2005557987134; Mean 252.70646016286125; Max. 49108.14; Valid 6263.0

Variable Format: numeric

Notes: UNF:6:CWHWGSos3wZhnmywEn4iZg==

f6956 Location:

Summary Statistics: Max. 42636.84; Valid 6263.0; StDev 1159.046462903758; Mean 254.13189366118473; Min. 0.0

Variable Format: numeric

Notes: UNF:6:ZdrpTdMG/eiCEbDEStEPWg==

f6956 Location:

Summary Statistics: Max. 42370.85; StDev 1129.0265292749066; Min. 0.0; Valid 6263.0; Mean 246.01309276704455

Variable Format: numeric

Notes: UNF:6:bgw4ehYoxZlqpS8tgdGKKg==

f6956 Location:

Summary Statistics: StDev 1148.7162870387067; Max. 43433.51; Mean 248.13890467826914; Valid 6263.0; Min. 0.0

Variable Format: numeric

Notes: UNF:6:oyk/XIJj73Kg51IFcTJ9NQ==

f6956 Location:

Summary Statistics: Min. 0.0; Valid 6263.0; Max. 42072.08; Mean 241.8800159667891; StDev 1240.492909460515;

Variable Format: numeric

Notes: UNF:6:Kr342ZGnQilgpCb1DCEuRQ==

f6956 Location:

Summary Statistics: StDev 1477.9508266079931; Mean 238.85330033530258; Max. 81187.71; Min. 0.0; Valid 6263.0

Variable Format: numeric

Notes: UNF:6:UgAMJoOjYrEhcXzElp7nPw==

f6956 Location:

Summary Statistics: StDev 1247.4268854385366; Max. 52178.05; Valid 6263.0; Min. 0.0; Mean 253.01381765926868

Variable Format: numeric

Notes: UNF:6:jmAlWrVrjWYjnrcme2DdBQ==

f6956 Location:

Summary Statistics: Max. 47240.47; Min. 0.0; Valid 6263.0; Mean 243.4968816860929; StDev 1143.5491735146024

Variable Format: numeric

Notes: UNF:6:pWfZ/LhC2c5kS5QrxwstvA==

f6956 Location:

Summary Statistics: Mean 232.81612645696956; Valid 6263.0; StDev 1354.6823201516345; Min. 0.0; Max. 67510.37;

Variable Format: numeric

Notes: UNF:6:H1WY1wYfzaMC8YI1OUniwg==

f6956 Location:

Summary Statistics: Min. 0.0; Max. 43495.1; Valid 6263.0; StDev 1317.3621495258012; Mean 239.84141146415456

Variable Format: numeric

Notes: UNF:6:CpueyCJ6ljj1M331T3NVig==

f6956 Location:

Summary Statistics: StDev 1106.772336376098; Valid 6263.0; Max. 41868.02; Min. 0.0; Mean 236.45378093565378;

Variable Format: numeric

Notes: UNF:6:r+pbXytBchoJnTWc9DOutA==

f6956 Location:

Summary Statistics: StDev 1091.6259040465816; Min. 0.0; Mean 226.90707967427755; Valid 6263.0; Max. 45147.22

Variable Format: numeric

Notes: UNF:6:KC6a34WiHcextAmvY4R3Mg==

f6955 Location:

Summary Statistics: StDev 2044.3195848095827; Max. 7132.0; Min. 1.0; Valid 5875.0; Mean 3604.6348936171325

Variable Format: numeric

Notes: UNF:6:nicTN8ymjP2DtlcdqGm6Hw==

f6955 Location:

Variable Format: character

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f6955 Location:

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f6955 Location:

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f6955 Location:

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f6955 Location:

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Label:

00_Readme.txt

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