Nanostructured lipid carriers for co-delivery of cannabidiol and piperine: insights from in vitro digestion and in vivo pharmacokinetic evaluationdoi:10.34622/datarepositorium/KV3JCURepositório de Dados da Universidade do Minho2025-12-021Vardanega, Renata; Lüdtke, Fernanda L.; Loureiro, Luís; Fernández-Carrera, Andrea; Santos, Joana; Venâncio, Armando; González-Fernández, África; Pinheiro, Ana C.; Vicente, António A., 2025, "Nanostructured lipid carriers for co-delivery of cannabidiol and piperine: insights from in vitro digestion and in vivo pharmacokinetic evaluation", https://doi.org/10.34622/datarepositorium/KV3JCU, Repositório de Dados da Universidade do Minho, V1, UNF:6:L07wrMc13aGqVm8nGSCjew== [fileUNF]Nanostructured lipid carriers for co-delivery of cannabidiol and piperine: insights from in vitro digestion and in vivo pharmacokinetic evaluationdoi:10.34622/datarepositorium/KV3JCUVardanega, RenataLüdtke, Fernanda L.Loureiro, LuísFernández-Carrera, AndreaSantos, JoanaVenâncio, ArmandoGonzález-Fernández, ÁfricaPinheiro, Ana C.Vicente, António A.101062938Repositório de Dados da Universidade do MinhoVardanega, RenataVardanega, Renata2025-05-28Chemistrypharmacokineticsbioavailabilitybioenhancerlipid-based systemscannabidiolpiperineThis dataset contains the experimental data that support the results of the manuscript: "Nanostructured lipid carriers for co-delivery of cannabidiol and piperine: insights from in vitro digestion and in vivo pharmacokinetic evaluation." This work was developed under the scope of the project CBDHIGHBIO - Strategies to modulate the bioavailability of cannabinoids in edible products: in vitro tests, cytotoxicity, and pre-clinical assessment to generate reliable data for regulatory agencies, funded by European Commission, Programme HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA), grant 101062938. The dataset contains protocols that describe the methodologies used to produce and characterise Nanostructured lipid carriers, to evaluate in vitro digestion and in vivo pharmacokinetics, experimental data, and statistical results. Detailed information about the files are available in the ReadMe file.<a rel="license" href="http://creativecommons.org/licenses/by-nc/4.0/"><img alt="Creative Commons Licence" style="border-width:0" src="https://i.creativecommons.org/l/by-nc/4.0/88x31.png" /></a><br />This work is licensed under a <a rel="license" href="http://creativecommons.org/licenses/by-nc/4.0/">Creative Commons Attribution-NonCommercial 4.0 International License</a>Until the article containg the data from this dataset is published, users can request access to the data by contacting renata.vardanega@ceb.uminho.ptrenata.vardanega@ceb.uminho.ptCitation of the correspondent paper should be included, if the dataset is used.CBDHIGHBIO_101062938_Protocol 8_DLS_Digestion.tab338text/tab-separated-valuesUNF:6:TMzIooNnB0JoWblUhBpm4w==CBDHIGHBIO_101062938_Protocol 8_DLS_Stability.tab716text/tab-separated-valuesUNF:6:A3gGewdw3tetxUdKpFGEkw==CBDHIGHBIO_101062938_Protocol 8_FFA.tab102text/tab-separated-valuesUNF:6:XffvWpCcaGCI411e6il4KQ==CBDHIGHBIO_101062938_Protocol 8_HPLC_Digestion.tab2211text/tab-separated-valuesUNF:6:Sq2k2kjfLbWgW905j6zaRw==CBDHIGHBIO_101062938_Protocol 9_UPLC-MS.tab6813text/tab-separated-valuesUNF:6:m/IiBGE/yClrocYsrNGTUw==NLCUNF:6:IRP54IUblJ2IYGExR4R9xg==PS(nm)222.027.02436.0.6.02213.9592592592591496.3770340030414496.0UNF:6:BULqfh8zhuj16tk2W22QPg==PDI9.024.01.0.0.3490.63145833333333330.164954533700670980.596UNF:6:xFBi7dePhBUvkMeIWm7BIw==Potencialzeta(mV)-1.49-6.10788888888889.27.06.0-47.62.5714.586994880407193UNF:6:U7OQqVGUnacBdB7g2WeCpA==EUNF:6:FhTVQoySFRspv3RkFZS/ag==PS(nm)473.6074699434194228.81752.030.0413.4642.26.3.0UNF:6:zjLilwRtG9Ga161tyV3//w==PDI0.243106998343688490.28630.03.0.0.59451.00.6152333333333333UNF:6:KV/5i5AqOP4scHm/zp8KWA==Potencialzeta(mV)30.0-36.2-38.19.-22.4-62.33.09.61386749835164UNF:6:do3fdJSsEPmWue4fCC/H0Q==NLCsUNF:6:8Q3Wspo/W8sTw4QtK/ClCQ==24hUNF:6:P2v32Xsjh5NNd44cIYQjvg==CUNF:6:7bZ8KdsXhDW85EWEU5K1OQ==DUNF:6:AYCl6iqT2HThfvJq6axBjQ==7daysUNF:6:3ROTZDis2Yjr3zrg4nkPrQ==FUNF:6:jDG4bmHQxrDREQ+7ZXfkrQ==GUNF:6:D4oWdktR/y1EkE3BWaYdTQ==14daysUNF:6:vudTpZpFHmd3suyasrR9bA==IUNF:6:lpk6ByXVuYhaoPNLngKRlA==JUNF:6:KGMd1Up8G/p5xybusimzcA==21daysUNF:6:02R6qhMPEX8NS43mUxCb8w==LUNF:6:QglbUgz7esdu5X/4bJSFHw==MUNF:6:U/evcnQZzLTzN2k7V9ddgA==30daysUNF:6:e6MZJ2LaJJDND8GYraNOjg==OUNF:6:9dZcyIGDn26A6NXZ9VSxsQ==PUNF:6:a37sE3Hx7EutLFJd8lkdjw==pHSTATASSAYUNF:6:HN1U5fSY0AnbKEYpGvAdYA==BUNF:6:75tsfz2FUOfABYpQ/snqTQ==ConcentraçaodeCBDcalculadaapartirdacurvaobtidaem18.06.2024(y=80175x+14243)UNF:6:gYiEL4O1Sl5k2LwxbU7jkA==BUNF:6:jwwFyi91b8r7stnns/4b9g==CUNF:6:Mupu7JVUrUsL6M35QODCAg==DUNF:6:E5mFoppL9dRDq84oueaTSw==EUNF:6:ZeNePd0oZjgEIOFsQFPaDA==FUNF:6:1Ypbpb/PW98NlDNYar/MHg==GUNF:6:AP1iogA3V6FL/aFT+A8NGw==HUNF:6:3aPL0WqZkgg/KAYlDzmXnQ==IUNF:6:amWpNbyJyyGmi1wVjLbRWA==JUNF:6:4PB1UjIlQL3exs2+WCh5gQ==KUNF:6:LSd+5WUSXnuG2p+XwotUMw==CBD-MaleUNF:6:0KiLHZQYbifZumTqwDFpvQ==BUNF:6:Yvi3/T4nI5PhrBqUnr2Klw==CUNF:6:DWuDzzU+BY/0XL/cizwuAQ==DUNF:6:xqPC0nCSL6J8YX16nqq65g==EUNF:6:hac0FqZQhWbaCap+t5C6Pg==FUNF:6:T/8cXr05eomSGOjCDizTNw==GUNF:6:tH4dAbdx0K8ZREU6pfYlFQ==HUNF:6:8ZbzjzOfNfRovgTzehImWw==IUNF:6:mU9fyGd4yJlnzrXbvdBScg==JUNF:6:kqOtIThMyj6X/GT0axEctQ==KUNF:6:qrFYd0kDgRA+HzSZPcNpSA==LUNF:6:3eJg5gole/MtmBYVc54OGQ==MUNF:6:tFR+9MQk8fK9pyFvBLp08g==00_ReadMe.txttext/plainCBDHIGHBIO-101062938_Protocol 8_v1.0.pdfapplication/pdfCBDHIGHBIO-101062938_Protocol 9_v1.0.pdfapplication/pdf